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Mechanism and pathogenesis of cerebral amyloidosis in APP transgenic mice

โœ Scribed by M. Jucker; A. Phinney; L. Bondolfi; D. Winkler; M. Tolnay; M. Calhoun; Christine Sturchler-Pierrat; M. Staufenbiel


Book ID
117411692
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
161 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract Amyloid deposits are one of the hallmarks of Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders. In transgenic mice modeling Alzheimer's pathology, the MR transverse relaxation time (__T__~2~) has been described to be modulated by amyloidosis. This modific