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Mechanical and energetic properties of rat papilary muscles: Whole muscles versus muscles split in the presence of 2,3-butanedione monoxime

โœ Scribed by Helen Kiriazis; Colin L Gibbs


Book ID
115985189
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
109 KB
Volume
24
Category
Article
ISSN
0022-2828

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The influence of 2,3-butanedione 2-monox
โœ D. F. A. Mckillop; N. S. Fortune; K. W. Ranatunga; M. A. Geeves ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer Netherlands ๐ŸŒ English โš– 850 KB

2,3-butanedione 2-monoxime (BDM) inhibits muscle contraction and actomyosin ATPase both in fibres and in solution. It is potentially useful as a tool for exploring weak interactions between actin and myosin. We have examined the effect of BDM on several key steps of the myosin subfragment-1 and acto