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Mecamylamine blocks the development of tolerance to nicotine in rats: implications for the mechanisms of tolerance

โœ Scribed by Sarah E. McCallum; A. R. Caggiula; Leonard H. Epstein; Saundra Saylor; Thomas Ploskina; Alan F. Sved


Publisher
Springer
Year
1999
Tongue
English
Weight
74 KB
Volume
141
Category
Article
ISSN
0033-3158

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Acute tolerance development to the diure
โœ Dr. Margareta Hammarlund; Lennart K. Paalzow ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 607 KB

Furosemide was given to rats as five different i.v. bolus doses (2.5-100mg kg-I), or as an i.v. infusion to a steady-state concentration in plasma of 14pgml-'. The urinary furosemide excretion rate (AAe/At) and the diuretic effect (volume of urine) were measured. A parallel shift in the excretion-re