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Acute tolerance to the locomotor stimulant effects of nicotine in the rat

✍ Scribed by Robert L. Hakan; Charles Ksir

Publisher
Springer
Year
1991
Tongue
English
Weight
671 KB
Volume
104
Category
Article
ISSN
0033-3158

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## Abstract Prolonged iontophoretic administrations of δ‐ and μ‐selective opioid receptor agonists were conducted in the hippocampus of rats, in order to study the possible development of acute tolerance to the excitatory effects of the opioids. Acute tolerance (AT) to the excitatory effects of the