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Measuring T cell receptor and T cell gene expression diversity in antigen-responsive human CD4+ T cells

✍ Scribed by Eugster, Anne; Lindner, Annett; Heninger, Anne-Kristin; Wilhelm, Carmen; Dietz, Sevina; Catani, Mara; Ziegler, Anette-G.; Bonifacio, Ezio

Book ID
121405797
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
563 KB
Volume
400-401
Category
Article
ISSN
0022-1759

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## Abstract The earliest T precursor population in the adult mouse thymus, considered to have the surface phenotype CD4^lo^8^βˆ’^3^βˆ’^44^+^25^βˆ’^Thy‐1^lo^ c‐kit^+^ (termed the low CD4 precursor), has been shown to have the capacity to produce B cells and dendritic cells, as well as T cells, and to have