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Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease

✍ Scribed by J.K. Morris; H. Zhang; A.A. Gupte; G.L. Bomhoff; J.A. Stanford; P.C. Geiger


Book ID
113503825
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
719 KB
Volume
1240
Category
Article
ISSN
0006-8993

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Asymmetries in turning and scanning were investigated in rats with different degrees of neostriatal dopamine depletion after unilateral injections of 6-hydroxydopamine into the substantia nigra. Animals with severe lesions, i.e., residual dopamine levels of <20%, spontaneously turned ipsiversive and