A Study of the Binding Energies of Efavi
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Pensri Srivab; Supa Hannongbua
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Article
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2008
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John Wiley and Sons
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English
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## Abstract A threeβlayered ONIOM model was used to study the interactions between efavirenz and the binding sites of HIVβ1 reverse transcriptase (RT): wildβtype and double mutant K103N/Y181C enzyme forms. Binding energies were determined and compared to describe the loss of activity of efavirenz w