✦ LIBER ✦

Design of nevirapine derivatives insensitive to the K103N and Y181C HIV-1 reverse transcriptase mutants

✍ Scribed by Saparpakorn, P.; Hannongbua, S.; Rognan, D.

Book ID: 125842057
Publisher: Taylor and Francis Group
Year: 2006
Tongue: English
Weight: 443 KB
Volume: 17
Category: Article
ISSN: 1062-936X
DOI: 10.1080/10659360600636147

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Thiotetrazole Alkynylacetanilides as Pot

Thiotetrazole Alkynylacetanilides as Potent and Bioavailable Non-Nucleoside Inhibitors of the HIV-1 Wild Type and K103N/Y181C Double Mutant Reverse Transcriptases.

✍ Alexandre Gagnon; et al. et al. 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 19 KB 👁 2 views

The Y181C Mutant of HIV-1 Reverse Transc

The Y181C Mutant of HIV-1 Reverse Transcriptase Resistant to Nonnucleoside Reverse Transcriptase Inhibitors Alters the Size Distribution of RNase H Cleavages †

✍ Archer, Richard H.; Wisniewski, Michele; Bambara, Robert A.; Demeter, Lisa M. 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 169 KB

A Study of the Binding Energies of Efavi

A Study of the Binding Energies of Efavirenz to Wild-Type and K103N/Y181C HIV-1 Reverse Transcriptase Based on the ONIOM Method

✍ Pensri Srivab; Supa Hannongbua 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 697 KB

## Abstract A three‐layered ONIOM model was used to study the interactions between efavirenz and the binding sites of HIV‐1 reverse transcriptase (RT): wild‐type and double mutant K103N/Y181C enzyme forms. Binding energies were determined and compared to describe the loss of activity of efavirenz w

Resistance to nevirapine of HIV-1 revers

Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions

✍ Giovanni Maga; Mario Amacker; Nancy Ruel; Ulrich Hübscher; Silvio Spadari 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 267 KB

A comparison of the ability of rilpiviri

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants

✍ Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph D Bauman, Heathe 📂 Article 📅 2012 🏛 BioMed Central 🌐 English ⚖ 648 KB

N-3 Substituted TSAO Derivatives as a Pr

N-3 Substituted TSAO Derivatives as a Probe to Explore the Dimeric Interface of HIV-1 Reverse Transcriptase

✍ Maria-Cruz Bonache; Cristina Chamorro; Sonsoles Velazquez; Erik De Clercq; Jan B 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 55 KB