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Measurement of reduced and total mercaptamine in urine using liquid chromatography with ultraviolet detection

✍ Scribed by Krzysztof Kuśmierek; Edward Bald

Book ID
101756515
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
114 KB
Volume
22
Category
Article
ISSN
0269-3879

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Cysteamine is currently used to treat children with the inherited disorder nephropathic cystinosis. A method for the quantitative determination of this aminothiol in human plasma is presented. Whole plasma was reduced with sodium borohydride to convert disulfides to thiols. Cysteamine was then separ