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Measurement of osteoclasts and bone resorption by automated image analysis

✍ Scribed by Somers, NM; Dunstan, CR; Lauren, PD; Evans, RA

Book ID
123297803
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
155 KB
Volume
13
Category
Article
ISSN
8756-3282

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## Abstract We confirmed the expression of cathepsin K, the most abundant and specific cysteine protease found in osteoclasts, at the mRNA level in most of our cases of breast cancer, and even at the protein level in bone metastatic lesions. Therefore, we investigated the functions of cathepsin K i