Measurement of 5-hydroxytryptophol and 5-hydroxyindoleacetic acid in human and rat brain and plasma
β Scribed by O. Beck; S. Borg; G. Jonsson; A. Lundman; P. Valverius
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 495 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1435-1463
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A method for simultaneous quantification of plasma homovanillic acid and 5-hydroxyindoleacetic acid has been developed, permitting more efficient neurochemical examinations of these often interrelated biogenic amine systems. Zinc sulphate and sodium hydroxide solutions were used for precipitating th
The accumulation of 5-HIAA and HVA in cerebrospinal fluid (CSF) was studied in eight healthy volunteers after oral administration of probenecid. Simulation indicated that a dose of 4.5 g probenecid should be used to achieve probenecid plasma concentrations between 200 and 400 pg/ml. Almost complete