Measles associated chromosome breakage
โ Scribed by Warren W. Nichols; Albert Levan
- Book ID
- 105135776
- Publisher
- Springer Vienna
- Year
- 1965
- Tongue
- English
- Weight
- 933 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1432-8798
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Immune deficiency and chromosome fragility are hallmarks of two human diseases, ataxia telangiectasia and Nijmegen breakage syndrome. The genes mutated in these diseases, ATM and NBSl, have been cloned and there has been considerable recent progress on deciphering the function of the protein product
An extended family is described in which three members had thrombocytopenia. These affected members had chromosomal changes resembling those found in Fanconi's anaemia, though they lacked the development defects associated with that syndrome. One had bone-marrow hypoplasia and died of squamous cell