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MDR1 polymorphisms are not associated with inflammatory bowel disease and response to therapy in Italian patients

✍ Scribed by O. Palmieri; A. Latiano; R. Valvano; R. D'Incà; M. Vecchi; G.C. Sturniolo; S. Saibeni; F. Bossa; T. Latiano; M. Devoto; A. Andriulli; V. Annese


Book ID
119632116
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
114 KB
Volume
38
Category
Article
ISSN
1590-8658

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## Background: To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to the efficacy of azathioprine in inducing remission in patients with Crohn's disease (CD). ## Methods: A cohort of 327 unrelated Spanish patients with CD recruited from