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MDR1 multidrug resistance gene expression is rapidly induced after exposure to doxorubicin,

Book ID
120871025
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2000
Weight
151 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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The most consistantly reported alteration of multidrug-resistant carcinoma cells is the overexpression of a membrane glycoprotein, termed P-glycoprotein. In this study we examined whether the strong intrinsic chemotherapy resistance of glial tumors might be related to the expression of the MDR1 gene