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269: Multidrug resistance gene MDR1 is transactivated by Oct4 to increase chemotherapy resistance

โœ Scribed by Wu, C.L.; Lu, C.S.; Shiau, A.L.

Book ID
125794039
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
66 KB
Volume
50
Category
Article
ISSN
0959-8049

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Is there evidence to claim or deny assoc
Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease?
โœ Elias Zintzaras ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 984 KB

Background: Inflammatory bowel disease (IBD) is a complex disease with a genetic background. Crohn's disease (CD) and ulcerative colitis (UC) are the two main types of IBD. There is indication that variants in the MDR1 gene are associated with development of IBD. However, the 20 published genetic as