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MDR1 C2005T polymorphism changes substrate specificity

✍ Scribed by Lijuan Liu; Lan Fan; Xiangdong Peng; Dongli Hu; Honghao Zhou

Book ID
105993435
Publisher
Springer
Year
2010
Tongue
English
Weight
290 KB
Volume
66
Category
Article
ISSN
0344-5704

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Synonymous single-nucleotide polymorphisms (SNPs) do not produce altered coding sequences, and therefore they are not expected to change the function of the protein in which they occur. We report that a synonymous SNP in the __Multidrug Resistance__ 1 ( __MDR__ 1) gene, part of a haplotype previousl