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MDM2 is Overexpressed and Regulated by the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Human Squamous Cell Carcinoma of Esophagus

✍ Scribed by Han-Shui Hsu; Hsin-Wu Chen; Chia-Li Kao; Min-Li Wu; Anna Fen-Yau Li; Tzu-Hao Cheng

Book ID
111773928
Publisher
Springer
Year
2010
Tongue
English
Weight
524 KB
Volume
18
Category
Article
ISSN
1068-9265

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✍ Igor B. Rosenwald; Michael J. Hutzler; Songtao Wang; Lou Savas; Armando E. Frair πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 617 KB

## BACKGROUND. When resting cells are stimulated by growth factors, an increase in protein synthesis follows that depends in part on two key eukaryotic translation initiation factors, 4E and 2␣ (eIF-4E and eIF-2␣, respectively). In the normal cell, expression and activity of both factors are incre