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Maximum likelihood refinement of electron microscopy data with normalization errors

✍ Scribed by Sjors H.W. Scheres; Mikel Valle; Patricia Grob; Eva Nogales; José-María Carazo


Book ID
116696946
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
529 KB
Volume
166
Category
Article
ISSN
1047-8477

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✍ Steven T. Garren 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 396 KB

The maximum likelihood estimator (MLE) of the correlation coefficient and its asymptotic properties are well-known for bivariate normal data when no observations are missing. The situation in which one of the two variates is not observed in some of the data is examined herein. The MLE of the correla