✦ LIBER ✦

Maturity-onset diabetes of the young (MODY)

✍ Scribed by T. Meissner; J. Marquard; E. Schober

Publisher: Springer-Verlag
Year: 2010
Tongue: German
Weight: 586 KB
Volume: 6
Category: Article
ISSN: 1860-9716
DOI: 10.1007/s11428-010-0543-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Maturity-onset diabetes of the young (MO

Maturity-onset diabetes of the young (MODY): how many cases are we missing?

✍ B. M. Shields; S. Hicks; M. H. Shepherd; K. Colclough; A. T. Hattersley; S. Ella 📂 Article 📅 2010 🏛 Springer 🌐 English ⚖ 242 KB

GCK and HNF1A mutations in Canadian fami

GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY)

✍ Henian Cao; Sanam Shorey; John Robinson; Daniel L. Metzger; Laura Stewart; Eliza 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 28 KB 👁 2 views

Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including

Identification of 21 novel glucokinase (

Identification of 21 novel glucokinase (GCK) mutations in UK and European Caucasians with maturity-onset diabetes of the young (MODY)

✍ K.L. Thomson; A.L. Gloyn; K. Colclough; M. Batten; L.I.S. Allen; F. Beards; A.T. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 32 KB 👁 2 views

## Maturity -onset diabetes of the young (MODY) resulting from mutations in the glucokinase (GCK) gene accounts for approximately 20% of MODY in the UK. W e have performed fluorescent single stranded conformation polymorphism (F-SSCP) analysis or direct sequencing of the GCK gene in 212 patients re

Identification of novel GCK and HNF1A/TC

Identification of novel GCK and HNF1A/TCF1 mutations and polymorphisms in German families with maturity-onset diabetes of the young (MODY)

✍ Dalia Toaima; Andrea Näke; Jutta Wendenburg; Kirsten Praedicow; Julia Rohayem; K 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 74 KB 👁 2 views

Maturity-onset diabetes of the young is a genetically heterogenous autosomal dominant form of diabetes mellitus, characterized by an early age at onset and a primary defect in beta-cell function. Forty families with a clinical presentation suggestive of MODY were screened for the most common MODY su

Three novel missense mutations in the gl

Three novel missense mutations in the glucokinase gene (G80S; E221K; G227C) in Italian subjects with maturity-onset diabetes of the young (MODY)

✍ Barbara Guazzini; Davide Gaffi; Davide Mainieri; Giuseppe Multari; Renzo Cordera 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 30 KB 👁 1 views

The maturity-onset diabetes of the young (MODY), an autosomal dominant form of non-insulin dependent diabetes mellitus (NIDDM), is caused by mutations in the glucokinase (GK, MODY 2) and in the hepatocyte nuclear factor 1 (MODY 3) and 4 (MODY1) genes. We have screened the glucokinase gene by the pol

R127W in HNF4α is a loss-of-function mut

R127W in HNF4α is a loss-of-function mutation causing maturity-onset diabetes of the young (MODY) in a UK Caucasian family

📂 Article 📅 2000 🏛 Springer 🌐 English ⚖ 34 KB