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Maturation-dependent regulation of protein kinase C activity by vitamin D3 metabolites in chondrocyte cultures

โœ Scribed by V. L. Sylvia; Z. Schwartz; L. Schuman; R. T. Morgan; S. Mackey; R. Gomez; B. D. Boyan


Book ID
118284259
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
886 KB
Volume
157
Category
Article
ISSN
0021-9541

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17b-Estradiol (E 2 ) regulates growth plate chondrocyte differentiation in both a sex-and cell maturation-dependent manner, and the sex-specific effects of E 2 appear to be mediated in part by membrane events. In this study, we examined whether E 2 regulates protein kinase C (PKC) in a cell-maturati