We have examined the effects of BMP-2 on the expression of bone matrix proteins in both human bone marrow stromal cells (HBMSC) and human osteoblasts (HOB) and their proliferation and mineralization. Both HBMSC and HOB express BMP-2/-4 type I and type II receptors. Treatment of these two cell types
Matrix Proteins versus Cytokines in the Regulation of Osteoblast Function and Bone Formation
✍ Scribed by M. Horowitz
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 65 KB
- Volume
- 72
- Category
- Article
- ISSN
- 1432-0827
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Estrogens have complex effects on the skeleton, including regulation of modeling and maintenance of bone mass, which vary with cell type and developmental stage. Osteoblasts are key regulators of skeletal matrix synthesis and degradation. However, whether osteocytes, osteoblasts or earl
## Abstract We investigated the effects of oscillatory flow in regulating the gene expressions of type I collagen (COL1, the main component of human bone tissues) and osteopontin (OPN, the key gene for calcium deposition) in human osteoblast‐like (MG‐63) cells, and the roles of mitogen‐activated pr
## Abstract Regulator of G‐protein signaling‐2 (RGS‐2) belongs to a novel family of GTPase‐activating proteins that rapidly turn‐off G‐protein coupled receptor signaling. RGS proteins contain a characteristic RGS domain by which they interact with the α‐subunit of G‐proteins and drive them into the