Vascular proliferative disorders are characterized by migration and proliferation of vascular smooth muscle cells (SMCs), loss of expression of SMC phenotype, and enhanced extracellular matrix synthesis (e.g., type I collagen). We report here that bone morphogenetic protein-7 (BMP-7), a member of th
โฆ LIBER โฆ
Osteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblasts
โ Scribed by L.-C.C. Yeh; R. Unda; J.C. Lee
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 283 KB
- Volume
- 185
- Category
- Article
- ISSN
- 0021-9541
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The bone morphogenetic protein (BMP)-2 is a potent osteoinductive signal, inducing bone formation in vivo and osteoblast differentiation from non-osseous cells in vitro. The runt domain-related protein Cbfa1/PEBP2โฃA/ AML-3 is a critical component of bone formation in vivo and transcriptional regulat