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Matrix Metalloproteinases As Novel Biomarkers and Potential Therapeutic Targets in Human Cancer

✍ Scribed by Roy, R.; Yang, J.; Moses, M. A.

Book ID
127263556
Publisher
American Society of Clinical Oncology
Year
2009
Tongue
English
Weight
701 KB
Volume
27
Category
Article
ISSN
0732-183X

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## Abstract Degradation of extracellular matrix is crucial for malignant tumour growth, invasion, metastasis and angiogenesis. Matrix metalloproteinases (MMPs) are a family of zinc‐dependent neutral endopeptidases collectively capable of degrading essentially all matrix components. Elevated levels