Matrix metalloproteinaseβ9 and spontaneo
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Jin-Moo Lee; Ke-Jie Yin; Idar Hsin; Shawei Chen; John D. Fryer; David M. Holtzma
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Article
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2003
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John Wiley and Sons
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English
β 175 KB
π 2 views
We examined the potential role of the extra-cellular matrix-degrading enzyme, matrix metalloproteinase-9 (MMP-9), in the pathogenesis of cerebral amyloid angiopathy (CAA)-induced spontaneous hemorrhage. The amyloid-beta peptide (Abeta) induced the synthesis, release and activation of MMP-9 in murine