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Matrix matching in liquid chromatography–mass spectrometry with stable isotope labelled internal standards—Is it necessary?

✍ Scribed by Amitha K. Hewavitharana


Book ID
108094362
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
109 KB
Volume
1218
Category
Article
ISSN
1873-3778

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The combined use of a so-called internal standard and the isotope-labeled derivatization reagent for the quantification of analytes for liquid chromatography-mass spectrometry (LC/MS) was further studied. The sample solution (containing the analytes and an internal standard) was derivatized with the