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Matrix assisted refolding of proteins by ion exchange chromatography

✍ Scribed by Christine Machold; Robert Schlegl; Wolfgang Buchinger; Alois Jungbauer


Book ID
118471260
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
360 KB
Volume
117
Category
Article
ISSN
0168-1656

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## Abstract A recombinant therapeutic protein expressed in __Escherichia coli__ in form of inclusion bodies was used as a model system for comparative studies on the refolding efficiencies obtained by continuous matrix‐assisted refolding or batch‐dilution in a stirred tank reactor. Due to the stron