Continuous Matrix-assisted Refolding of
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R. Schlegl; R. Necina; A. Jungbauer
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Article
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2005
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John Wiley and Sons
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English
⚖ 331 KB
## Abstract A recombinant therapeutic protein expressed in __Escherichia coli__ in form of inclusion bodies was used as a model system for comparative studies on the refolding efficiencies obtained by continuous matrix‐assisted refolding or batch‐dilution in a stirred tank reactor. Due to the stron