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Matrix-assisted laser desorption of neutral organic molecules

✍ Scribed by Gary R. Kinsel; Josef Lindner; Jürgen Grotemeyer

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
574 KB
Volume
26
Category
Article
ISSN
1076-5174

No coin nor oath required. For personal study only.

✦ Synopsis

Dedicated to Professor Dr G. Spiteller on the occasion of his 60th birthday Results of initial investigations of matrix-assisted laser desorption (LD) of neutral molecules are presented The investigations were performed using gramicidine D as the test molecule, since both the wavelengtb-dependent LD behaviour and the ionization and fragmentation behaviour of the pure material had been studied previously. Comparisons between previously reported results for the pure compound and the matrix mixtures used in these studies are made. The results show that, whereas no signal could be observed from the pure sample material at 0011resonant desorbing wavelength, addition of a strongly absorbing matrix to the sample initiated LD of abundant intact neutral sample molecules. The results are d i s c d in the light of previous studies of the LD mechanism and support an explosive, mechanically driven model for the LD process.

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