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Mating-type switching in yeast is induced by thymine nucleotide depletion

✍ Scribed by Kunz, B. A. ;Taylor, G. R. ;Haynes, R. H.


Publisher
Springer
Year
1985
Tongue
English
Weight
339 KB
Volume
199
Category
Article
ISSN
0026-8925

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✦ Synopsis


Thymidylate biosynthesis was inhibited in a haploid heterothallic strain of Saccharomyces cerevisiae. When the treated cells were mixed with a haploid strain of the same mating-type, there was an increase in the recovery of diploid colonies. Genetic and biochemical analyses demonstrated that the diploid clones arose as a consequence of induced mating-type interconversion.


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