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Mathematical models for multidrug resistance and its reversal

โœ Scribed by Seth Michelson


Book ID
104922292
Publisher
Springer
Year
1993
Tongue
English
Weight
844 KB
Volume
12
Category
Article
ISSN
0920-9069

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The multidrug-resistance (MR) status of camptothecin (CPT) was investigated in colon adenocarcinoma HT29 cells, leukemia K562, and breast carcinoma MCF7 cells expressing P-glycoprotein (Pgp) and/or MR-associated protein (MRP1). The concentration that induced 50% growth inhibition (IC(50)) against CP