Mathematical modeling and sustained release property of a 5-fluorouracil imprinted vehicle
β Scribed by Kan, Wentao; Li, Xin
- Book ID
- 121698547
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 795 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0014-3057
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The release rate of 5-fluorouracil (5-FU) from lipid-coated nanoparticles (LNPs) was determined to develop a respirable delivery system for use as adjuvant (postsurgery) therapy for lung cancer. LNPs were prepared by spray drying, and the in vitro release was measured by microdialysis. The compositi
The release rate of 5-fluorouracil (5-FU) from liposomes, microspheres, and lipid-coated nanoparticles (LNPs) was determined by microdialysis to investigate their use as a respirable delivery system for adjuvant (postsurgery) therapy of lung cancer. 5-FU was incorporated into liposomes using thin fi