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Mathematical Analysis of Bursting Mechanisms in Pancreatic β-Cells

✍ Scribed by Cha, Chae Young; Nakamura, Yasuhiko; Santos, Enrique; Noma, Akinori


Book ID
119207841
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
38 KB
Volume
100
Category
Article
ISSN
0006-3495

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Secretion of insulin by electrically coupled populations of pancreatic -cells is governed by bursting electrical activity. Isolated -cells, however, exhibit atypical bursting or continuous spike activity. We study bursting as an emergent property of the population, focussing on interactions among th