To evaluate the potential utility of free beta (hCG) and beta-core (hCG) in a prenatal screening protocol for Down syndrome we analysed these markers in dried maternal urine specimens from 163 control, 13 Down syndrome and 5 trisomy 18 pregnancies from 8 to 25 weeks' gestation. All results are repor
โฆ LIBER โฆ
Maternal urine screening using dried specimen technology: Comparison of free-beta HCG and beta core fragment
โ Scribed by T Hallahan; D. Krantz; B. Brambati; L. Tului; P. Buchanan; F. Orlandi; V. Klein; J. Larsen; J. Macri
- Book ID
- 113984928
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 133 KB
- Volume
- 176
- Category
- Article
- ISSN
- 1097-6868
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High free beta human chorionic gonadotropin ( -hCG) and low alpha-fetoprotein (AFP) levels were found in 47 Asian Down's syndrome pregnancies (median values 2โข79 and 0โข77 MOM, respectively). At a 5 per cent false-positive rate, free -hCG alone would identify 46โข8 per cent of Down's syndrome pregnanc