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Maternal smoking and the epidemic of testicular cancer—A nested case–control study

✍ Scribed by Andreas Pettersson; Olof Akre; Lorenzo Richiardi; Anders Ekbom; Magnus Kaijser

Publisher
John Wiley and Sons
Year
2007
Tongue
French
Weight
57 KB
Volume
120
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

For no apparent reason, the incidence of testicular cancer has increased to epidemic proportions in many countries. Pregnancy smoking has been suggested to be a cause. Previous analytical studies have been negative, but the inherent difficulties in retrospective assessment of this exposure have led to no definite conclusion. We have conducted a population‐based case–control study on 192 cases of testicular germ‐cell cancer—born in Sweden in 1973 onwards and aged ≥15 at cancer diagnosis—and 494 matched controls, where data on maternal smoking were collected during pregnancy. We found no association with testicular cancer for maternal smoking during pregnancy (OR, 0.91; 95% CI, 0.64–1.30), and there was no evidence of a dose–response effect. We conclude that the epidemic rise in testicular cancer in many populations is not due to the surge in smoking among women. © 2007 Wiley‐Liss, Inc.

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