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Mast cell degranulation – a mechanism for the anti-arrhythmic effect of endothelin-1?

✍ Scribed by SK Walsh; KA Kane; CL Wainwright

Book ID
111219151
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
357 KB
Volume
157
Category
Article
ISSN
0007-1188

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Endothelin-1 (ET-1), originally described as a vasoconstrictor, is now known to be involved in pathogenesis of various disorders including vascular, inflammatory, and fibrotic diseases. Recent studies suggest that mast cells are also involved in the same pathological conditions. In this study, we te