For metabolic studies the fragmentation of a novel endothelin receptor antagonist, Bosentan, was investigated using ionspray tandem mass spectrometry. Bosentan belongs to the sulphonamide class and a complicated and unexpected fragmentation at low energy, involving a radical fragmentation of an even
โฆ LIBER โฆ
Mass spectrometry at low electron beam energies: A sensitive probe of vibrational excitation
โ Scribed by V.T. Amorebieta; A.J. Colussi
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 286 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0009-2614
No coin nor oath required. For personal study only.
โฆ Synopsis
It 1s shown that the imgmcnlrttlon palrcrn of fKsH& produced by low-cncrgy clccrron lmprcl mmwrion m ZI modulated beam mass spectrometer IS 3 SCIISI~IVC lunction of 111~ mWd gas kmpcraturc. Under these condltlons, mats spcctromcfry lends 1tsclCqui1c gcncrrdly IO the study of cncrg dcposulon and exchang m processes mvolvmg polyatomlcs
๐ SIMILAR VOLUMES
Fragmentation of Bosentan ยฎ (Ro 47-0203)
โ
G. Hopfgartner; W. Vetter; W. Meister; H. Ramuz
๐
Article
๐
1996
๐
John Wiley and Sons
๐
English
โ 472 KB
๐ 1 views
The dissociation of 13CH and 12CH2 molec
โ
T. Schulze-Kรถnig; M. Seiler; M. Suter; L. Wacker; H.-A. Synal
๐
Article
๐
2011
๐
Elsevier Science
๐
English
โ 679 KB