Mass spectrometric study of dimethyl-substituted spiro[4.5]decanes and spiro[5.5]undecanes
โ Scribed by G. V. Rusinova; L. S. Golovkina; N. B. Novikova; I. M. Sokolova; Al. A. Petrov
- Book ID
- 112448377
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 312 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1573-9171
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## Abstract A number of terminally substituted spiranes were prepared from 9โpentylโ3โspiro[5.5]undecanone (7), which was obtained in a fiveโstep synthesis starting from 4โpentylcyclohexanone (1), using an intramolecular cyclisation with 4โtoluenesulfonylmethyl isocyanide (TosMIC) as a key step. By
Synthesis and Characterization of Optically Active Spiro[4.5]decanes. -Three different dienes (I), substituted with a chiral auxiliary at the 1-position, and dienophiles (II) or (VII) undergo a Diels-Alder cycloaddition with quite good diastereofacial selectivity. The Si-exo and Re-endo diastereomer