Mass spectrometric characterization of substituted 2-thiazolin-4-one derivatives

✍ Scribed by Gianluca Giorgi; Laura Salvini; Orazio A. Attanasi; Paolino Filippone; Stefania Santeusanio

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 141 KB
• Volume: 37
• Category: Article
• ISSN: 1076-5174
• DOI: 10.1002/jms.329

✦ Synopsis

Abstract

Electron ionization mass spectrometry was used for the structural characterization of substituted 2‐thiazolin‐4‐one derivatives in the gas phase. The compounds follow common fragmentation pathways, producing ions whose abundances are dependent on the chemical nature of the substituent at position 2. Collision‐induced dissociation tandem mass spectrometric experiments, carried out on both molecular ions and fragment ions produced in the source, allowed the elucidation of gas‐phase decompositions. The presence of tautomeric forms is suggested for some ionic species. Rapid identification of a primary or secondary amine moiety at position 2 of the thiazoline ring can be achieved by the detection of characteristic fragmentations occurring both in the ion source and under the collision‐induced dissociation regime. Copyright © 2002 John Wiley & Sons, Ltd.