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Mass-spectrometric behavior and PMR spectra of 9-(2-R-1,3-dioxan-5-yl)purines

✍ Scribed by Yu. Yu. Samitov; I. N. Goncharova; N. P. Ramzaeva; P. B. Terent'ev


Book ID
112355189
Publisher
Springer US
Year
1984
Tongue
English
Weight
543 KB
Volume
20
Category
Article
ISSN
0009-3122

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## Abstract Stereoselective synthesis of 5‐[2‐(guanin‐9‐yl)‐ and 5‐[2‐(2‐aminopurin‐9‐yl)ethyl]‐2‐D‐ribo‐(1β€²,2β€²,3β€²,4′‐tetrahydroxybutyl)‐1,3‐dioxane, 2‐5, as potential prodrugs of penciclovir, has been accomplished in six steps from readily available 2,3,4,5‐tetra‐__O__‐acetyl‐__aldehydo__‐D‐ribose