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Mass spectra of the trimethylsilyl ethers of some 3β-hydroxy-Δ5-C21 steroids

✍ Scribed by D. J. Harvey; B. S. Middleditch; C. J. W. Brooks

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Volume
9
Category
Article
ISSN
1076-5174

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✦ Synopsis

The mass spectra of the trimethylsilyl derivatives of 22 3P-hydroxy-A5-pregnenes have been examined with the aid of deuterium labelling and high resolution mass measurements. The influence of additional hydroxy and keto substituents on the characteristic fragment ions is discussed and fragmentation mechanisms for several ions characteristic of hydroxylation at specific sites (11 and 16) are proposed.

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A novel fragmentation of trimethylsilyl
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