## Abstract Twentyβthree patients in various cytological subgroups of blast phase of Ph^1^βpositive chronic myeloid leukaemia were investigated cytogenetically. The correlation between prognosis and the cytological and cytogenetic features of blast cells was studied. The best prognosis was found in
?Masked? Ph1-chromosome in chronic myelogenous leukaemia (CML)
β Scribed by Verma, Ram S. ;Dosik, Harvey
- Publisher
- Springer-Verlag
- Year
- 1985
- Weight
- 278 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1432-0584
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Four cases of C.G.L. in which banding of the Ph1 chromosome was performed were found to have variation from the usual 9/22 translocation pattern. All 4 cases showed a rearrangement involving at least 3 chromosomes, 2 of which were a9 and a22. One of these cases had in addition an XYY karyotype in th
A proportion of cases of chronic myelogenous leukaemia (CML) has been described either (1) with a variant translocation, or (2) without the apparent involvement of both 9q34 and 22qll (Ph-negative CML). All variant translocations have been further demonstrated to be complex implicating 9q34,22q11, p
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