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Structural rearrangements associated with the Ph1chromosome in chronic granulocytic leukaemia

✍ Scribed by A. M. Potter; J. C. Sharp; M. J. Brown; R. J. Sokol

Publisher
Springer
Year
1975
Tongue
English
Weight
377 KB
Volume
29
Category
Article
ISSN
0340-6717

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✦ Synopsis

Four cases of C.G.L. in which banding of the Ph1 chromosome was performed were found to have variation from the usual 9/22 translocation pattern. All 4 cases showed a rearrangement involving at least 3 chromosomes, 2 of which were a9 and a22. One of these cases had in addition an XYY karyotype in the bone marrow.

📜 SIMILAR VOLUMES

Prognostic value of chromosomal findings
Prognostic value of chromosomal findings in the blast phase of Ph1-positive chronic myeloid leukaemia (CML)
✍ ÉVa Oláh; Kálmán Rák 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 584 KB

## Abstract Twenty‐three patients in various cytological subgroups of blast phase of Ph^1^‐positive chronic myeloid leukaemia were investigated cytogenetically. The correlation between prognosis and the cytological and cytogenetic features of blast cells was studied. The best prognosis was found in