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Markers of squamous cell carcinoma in sarco/endoplasmic reticulum Ca2+ ATPase 2 heterozygote mice keratinocytes

✍ Scribed by Jeong Hee Hong; Yu-Mi Yang; Hyun Sil Kim; Syng-Ill Lee; Shmuel Muallem; Dong Min Shin


Book ID
118492354
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
884 KB
Volume
103
Category
Article
ISSN
0079-6107

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## Abstract Mice with a heterozygous deletion of the __Atp2a2__ gene (__Atp2a2__^+/βˆ’^) encoding SERCA2 spontaneously develop SCCs of the skin and upper digestive tract, including the oral cavity. To elucidate the contribution of __ATP2A2__ to human oral carcinogenesis, we analyzed genetic and epige