Involvement of Sarco/endoplasmic Reticulum Ca2+ATPases in Cell Function and the Cellular Consequences of Their Inhibition
β Scribed by A. Hussain; G. Inesi
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 64 KB
- Volume
- 172
- Category
- Article
- ISSN
- 0022-2631
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Cress (Lepidium sativum L.) roots were treated with 20 microM cyclopiazonic acid (CPA), an inhibitor of the Ca(2+)-transporting ATPases present in the sarcoplasmic/endoplasmic reticulum of animals and the endoplasmic reticulum of plants, in order to investigate its effect on the gravitropic response
## Abstract Studies with inβvitroβcultured neurons treated with amyloidβΞ² (AΞ²) peptides demonstrated neuronal loss by apoptosis that is due, at least in part, to the perturbation of intracellular Ca^2+^ homeostasis. In addition, it was shown that an endoplasmic reticulum (ER)βspecific apoptotic pat