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Marked effects of islets of Langerhans on growth of human pancreatic cancer cells revealed by co-culture


Book ID
122756425
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
145 KB
Volume
108
Category
Article
ISSN
0016-5085

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5-hydroxytryptamine (5-HT) is a mitogen for fibroblasts, vascular smooth muscle cells, renal mesangial cells, and jejunal crypt cells. The human carcinoid cell line (termed BON) that we established in our laboratory from a pancreatic carcinoid tumor produces and secretes 5-HT. In this study, therefo