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March separate, strike together — Role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

✍ Scribed by Eckert, Anne; Nisbet, Rebecca; Grimm, Amandine; Götz, Jürgen

Book ID
122743365
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
847 KB
Volume
1842
Category
Article
ISSN
0925-4439

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## Abstract Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to t