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Mapping the structural determinants of presynaptic neurotoxicity of snake venom phospholipases A2

✍ Scribed by Petra Prijatelj; Zala Jenko Pražnikar; Toni Petan; Igor Križaj; Jože Pungerčar


Book ID
116922019
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
542 KB
Volume
51
Category
Article
ISSN
0041-0101

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Neurotoxic activity of Gln49 phospholipa
✍ Yan Chang; Yingxue Li; Yongming Bao; Lijia An 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 298 KB

A novel neurotoxic protein phospholipase A 2 (PLA 2 ), molecular weight 13 881.83 Da, has been isolated from snake venom of Gloydius ussuriensis, named as Gln49-PLA 2 , which shows weak lethal toxic, myotoxic and apparent anticoagulant activity, but lacks phospholipase activity. The Gln49-PLA 2 obvi