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Mapping the effects of the selective dopamine D2/D3 receptor agonist quinelorane using pharmacological magnetic resonance imaging

✍ Scribed by M.D. Ireland; A.S. Lowe; C. Reavill; M.F. James; R.A. Leslie; S.C.R. Williams


Book ID
116786958
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
714 KB
Volume
133
Category
Article
ISSN
0306-4522

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L-dopa remains the most common treatment for Parkinson's disease. However, there is considerable interest in D3/D2 receptor agonists such as the novel agent S32504, since they exert antiparkinsonian properties in the absence of dyskinesia. An important question concerns the roles of D2 vs. D3 recept