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Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry

✍ Scribed by Yunsheng Hsieh; Jiwen Chen; Walter A. Korfmacher

Book ID
113941202
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
842 KB
Volume
55
Category
Article
ISSN
1056-8719

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## Abstract MALDI‐imaging mass spectrometry (IMS) has been shown to be a powerful tool to study drug distributions in organ tissue as well as whole animal bodies. Nevertheless, not all drugs are amenable to MALDI while others may be limited by poor sensitivity poor sensitivity. The use of chemical