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Mapping of the genes for tubular basement membrane antigen and a submaxillary gland protease in the rat

โœ Scribed by Kozo Matsumoto; Eileen McCafferty; Eric G. Neilson; David L. Gasser


Publisher
Springer-Verlag
Year
1984
Tongue
English
Weight
397 KB
Volume
20
Category
Article
ISSN
0093-7711

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โœฆ Synopsis


The gene for tubular basement membrane (Tbm) antigen in the rat has been mapped relative to other markers in the first linkage group, and a polymorphic locus for a submaxillary gland protease, Tamase-1, has been identified. The hair-loss mutation fuzzy has also been mapped and occupies a position which is similar to that of the frizzy gene in the mouse. There are now at least five, and possibly six, genetic loci distributed over more than 30 centimorgans in the first linkage group of the rat which map in positions of approximate homology on the seventh chromosome of the mouse.


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A procedure was described for the rapid determination of glucosamine and galactosamine in total acid hydrolyzate of rat renal glomerular basement membrane (GBM) by the use of amino acid analyzer. Glucosamine and galactosamine, as well as other amino acids in glycoprotein hydrolyzate, were well ident